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2020

 

• Preclinical Anticancer Activity of an Electron‐Deficient Organoruthenium(II) Complex, J. J. Soldevila‐Barreda, M. Azmanova, A. Pitto‐Barry, P. A. Cooper, S. D. Shnyder, N. P. E. Barry, ChemMedChem, 2020, doi: 10.1002/cmdc.202000096.
• The Sound of Chemistry: Translating Infrared Wavenumbers into Musical Notes, N. Garrido, A. Pitto-Barry, J. J. Soldevila Barreda, A. Lupan, L. Comerford Boyes, W. Martin, and N. P. E. Barry, Journal of Chemical Education, 2020, 97, 703-709.

2019

• Effect of Temperature on the Nucleation and Growth of Precious Metal Nanocrystals, A. Pitto-Barry and N. P. E. Barry,  Angewandte Chemie International Edition, 2019, 58, 18482-18486.
• Anticancer activity of electron‐deficient metal complexes against colorectal cancer in vitro models
  M. Azmanova, J. J. Soldevila-Barreda, H. Bani Hani, R.M. Lord, A. Pitto-Barry, S. Picksley, and N. P. E. Barry, ChemMedChem, 2019, DOI: 10.1002/cmdc.201900528
• Influence of boron doping on the dynamics of formation of Os metal nanoclusters on graphitic surfaces
  A. Pitto-Barry and N. P. E. Barry, Chemical Communications, 2019, 55, 6038-6041.

2018

• Controlled Release of Carbon Monoxide from a Pseudo Electron-Deficient Organometallic Complex
  A. Pitto-Barry and N. P. E. Barry, ACS Omega, 2018, 3, 15623-15627.
• In Vivo Selectivity and Localization of Reactive Oxygen Species (ROS) Induction by Osmium Anticancer Complexes That Circumvent Platinum Resistance
  J. P. C. Coverdale, H. E. Bridgewater, J.-I. Song, N. A. Smith, N. P. E. Barry, I. Bagley, P. J. Sadler, and I. Romero-Canelon, Journal of Medicinal Chemistry, 2018, 61, 9246-9255.
• Exploiting topology-directed nanoparticle disassembly for triggered drug delivery
  M. C. Arno, R. J. Williams, P. Bexis, A. Pitto-Barry , N. Kirby, A. P. Dove, R. K. O’Reilly, Biomaterials , 2018, 180, 184-192.
• New Class of Hybrid Materials for Detection, Capture, and “On-Demand” Release of Carbon Monoxide
  A. Pitto-Barry, A. Lupan, C. Ellingford, A. A. A. Attia, and N. P. E. Barry, ACS Applied Materials and Interfaces, 2018, 10, 13693-13701.
• Structural determinants of the stability of enzyme‐responsive polyion complex (PIC) nanoparticles targeting Pseudomonas aeruginosa Elastase
  I. Insua, M. Petit, L. D. Blackman, R. Keogh, A. Pitto-Barry, R. K. O’Reilly, A. F. Peacock, A.-M. Krachler, F. Fernandez-Trillo, ChemNanoMat, 2018, 4, 807-814
• Schizophrenia: synthetic strategies and recent advances in drug design
  M. Azmanova, A. Pitto-Barry, and N. P. E. Barry, Medicinal Chemistry Communications, 2018, 9, 759-782.

  2017

• Anti-inflammatory activity of electron-deficient organometallics
  J. Zhang, A. Pitto-Barry, L. Shang, and N. P. E. Barry, Royal Society Open Science, 2017, 4, 170786.
• Halide Control of N,N-Coordination versus N,C-Cyclometalation and Stereospecific Phenyl Ring Deuteration of Osmium(II) p-Cymene Phenylazobenzothiazole Complexes
  R. J. Needham, A. Habtemariam, N. P. E. Barry, G. Clarkson, and P. J. Sadler, Organometallics, 2017, 36, 4367-4375.
• Controlled fabrication of osmium nanocrystals by electron, laser and microwave irradiation and characterisation by microfocus X-ray absorption spectroscopy
  A. Pitto-Barry, K. Geraki, M. D. Horbury, V. G. Stavros, J. F. W. Mosselmans, R. I. Walton, P. J. Sadler, and N. P. E. Barry, Chemical Communications, 2017, 53, 12898-12901.
• Pseudo electron-deficient organometallics: limited reactivity towards electron-donating ligands
  A. Pitto-Barry, A. Lupan, M. Zegke, T. Swift, A. A. A. Attia, R. M. Lord, and N. P. E. Barry, Dalton Transactions,  2017, 46, 15676-15683.

• 1D vs. 2D shape selectivity in the crystallization-driven self-assembly of polylactide block copolymers
  M. Inam, G. Cambridge, A. Pitto-Barry, Z. P. L. Laker, N. R. Wilson, R. T. Mathers, A. P. Dove, and R. K. O’Reilly, Chemical Science, 2017, 8, 4223-4230, part of the themed collection ISACS21: Challenges in Nanoscience.
  
• The hydrolytic behavior of N,N’-(dimethylamino) ethyl acrylate-functionalized polymeric stars
  M. S. Rolph, A. Pitto-Barry, and R. K. O’Reilly, Polymer Chemistry, 2017, 8, 5060-5070.

2016

• CO₂/pH-responsive particles with built-in fluorescence read-out
  A. B. Mabire, Q. Brouard, A. Pitto-Barry, R. J. Williams, H. Willcock, N. Kirby, E. Chapman, R. K. O’Reilly, Polymer Chemistry, 2016, 7, 5943-5948
• Pyrene: The Guest of Honor
  N. P. E. Barry, B. Therrien, in Organic Nanoreactors, Samahe Sadjadi, Oxford: Elsevier, 2016, 421-461.
• Nanoparticles of chitosan conjugated to organo-ruthenium complexes
  Y. Wang, A. Pitto-Barry, A. Habtemariam, I. Romero-Canelon, P J. Sadler, N. P. E. Barry, Inorganic Chemistry Frontiers, 2016, 3, 1058-1064.
• Micellar nanoparticles with tuneable morphologies through interactions between nucleobase-containing synthetic polymers in aqueous solution
  Z. Hua, A. Pitto-Barry, Y. Kang, N. Kirby, T. R. Wilks, R. K. O’Reilly, Polymer Chemistry, 2016, 7, 4254-4262.
• Use of complementary nucleobase-containing synthetic polymers to prepare complex self-assembled morphologies in water
  Y. Kang, A. Pitto-Barry, M. S. Rolph, Z. Hua, I. Hands-Portman, N. Kirby and R. K. O’Reilly, Polymer Chemistry, 2016, 7, 2836-2846.
• Cyclic graft copolymer unimolecular micelles: Effects of cyclization on particle morphology and thermoresponsive behavior
  R. J. Williams, A. Pitto-Barry, N. Kirby, A. P. Dove, and R. K. O’Reilly, Macromolecules, 2016, 49, 2802-2813.
• Core functionalization of semi-crystalline polymeric cylindrical nanoparticles using photo-initiated thiol–ene radical reactions
  L. Sun, A. Pitto-Barry, A. W. Thomas, M. Inam, K. Doncom, A. P. Dove, and R. K. O’Reilly, Polymer Chemistry, 2016, 7, 2337-2341
  
• Dynamics of formation of Ru, Os, Ir and Au metal nanocrystals on doped graphitic surfaces
  A. Pitto-Barry, P. J. Sadler, N. P. E. Barry, Chemical Communications, 2016, 52, 3895-3898.
• The synthesis and unexpected solution chemistry of thermochromic carborane-containing osmium half-sandwich complexes
  A. Pitto-Barry, A. South, A. Rodger, N. P. E. Barry, Dalton Transactions, 2016, 45, 1763-1768.
• Retaining Individualities: the Photodynamics of Self-Ordering Porphyrin Assemblies
  W. Quan, A. Pitto-Barry, L. Baker, E. Stulz, R. M. Napier, R. K. O’Reilly and V. Stavros, Chemical Communications, 2016, 52, 1938-1941.

2015

• Synthesis and controlled growth of osmium nanoparticles by electron irradiation
  A. Pitto-Barry, L. M. A. Perdigao, M. Walker, J. Lawrence, G. Costantini, P. J. Sadler, N. P. E. Barry, Dalton Transactions, 2015, 44, 20308-20311, part of Dalton Transactions’ HOT articles from 2015.
  

• The copolymer blending method: a new approach for targeted assembly of micellar nanoparticles
  D. W. Wright, J. P. Patterson, A. Pitto-Barry, A. Lu, N. Kirby, N. C. Gianneschi, C. Chassenieux, O. Colombani, R. K. O’Reilly, Macromolecules, 2015, 48, 6516-6522
• Amphiphilic block copolymer self-assemblies of poly(NVP)-b-poly(MDO-co-vinyl esters): tunable dimensions and functionalities
  G. G. Hedir, A. Pitto-Barry, A. P. Dove, R. K. O’Reilly, Journal of Polymer Science, Part A: Polymer Chemistry, 2015, 53, 2699-2710.
• Self-assembly of temperature-responsive protein-polymer bioconjugates
  D. Moatsou, J. Li, A. Ranji, A. Pitto-Barry, I. Ntai, M. C. Jewett, R. K. O’Reilly, Bioconjugate Chemistry, 2015, 26, 1890-1899.
  
• Osmium Atoms and Os2 Molecules Move Faster on Selenium-Doped Compared to Sulfur-Doped Boronic Graphenic Surfaces
  N. P. E. Barry, A. Pitto-Barry, J. Tran, S. E. F. Spencer, A. M. Johansen, A. M. Sanchez, A. P. Dove, R. K. O’Reilly, R. J. Deeth, R. Beanland, P. J. Sadler, Chemistry of Materials, 2015, 27, 5100-5105.
• RAFT dispersion polymerization: A method to tune the morphology of thymine-containing self-assemblies
  Y. Kang, A. Pitto-Barry, A. Maitland, R. K. O’Reilly, Polymer Chemistry, 2015, 6, 4984-4992.
• Arene ruthenium dithiolato–carborane complexes for boron neutron capture therapy (BNCT)
  I. Romero-Canelón, B. Phoenix, A. Pitto-Barry, J. Tran, J. J. Soldevila-Barreda, N. Kirby, S. Green, P. J. Sadler, N. P. E. Barry, Journal of Organometallic Chemistry, 2015, 796, 17-25, dedicated to Professor Georg Süss-Fink on the occasion of his 65^th birthday.
• Complementary light scattering and synchrotron small-angle X-ray scattering studies of the micelle-to-unimer transition of polysulfobetaines
  K. E. B. Doncom, A. Pitto-Barry, H. Willcock, A. Lu, B. E. McKenzie, N. Kirby and R. K. O’Reilly, Soft Matter, 2015, 11, 3666-3676.
• Tuning the aggegation behaviour of pH-responsive micelles by copolymerization
  D. B. Wright, J. P. Patterson, A. Pitto-Barry, P. Cotanda, C. Chassenieux, O. Colombani and R. K. O’Reilly, Polymer Chemistry, 2015, 6, 2761-2768.
• Exploiting nucleobase-containing materials – from monomers to complex morphologies using RAFT dispersion polymerization
  Y. Kang, A. Pitto-Barry, H. Willcock, W-D. Quan, N. Kirby, A. M. Sanchez and R. K. O’Reilly, Polymer Chemistry, 2015, 6, 106-117

2014

• Designing Supramolecular Liquid-Crystalline Hybrids from Pyrenyl-Containing Dendrimers and Arene Ruthenium Metalla-Cycles
  A. Pitto-Barry, N. P. E. Barry, V. Russo, B. Heinrich, B. Donnio, B. Therrien, and R. Deschenaux, Journal of the American Chemical Society, 2014, 136, 17616-17625.
• Structural reorganization of cylindrical nanoparticles triggered by polylactide stereocomplexation
  L. Sun, A. Pitto-Barry, N. Kirby, T. Schiller, A. Sanchez, M. Dyson, J. Sloan, N. Wilson, R. K. O’Reilly, and A. P. Dove, Nature Communications, 2014, 5, 5746.
• Dual effect of thiol addition on fluorescent polymeric micelles: ON-to-OFF emissive switch and morphology transition
  A. Mabire, M. P. Robin, H. Willcock, A. Pitto-Barry, N. Kirby and R. K. O’Reilly, Chemical Communications, 2014, 50, 11492-11495.
• Precious metal carborane polymer nanoparticles: characterisation of micellar formulations and anticancer activity
  N. P. E. Barry, A. Pitto-Barry, I. Romero-Canelón, J. Tran, J. J. Soldevila-Barreda, I. Hands-Portman, C. J. Smith, N. Kirby, A. P. Dove, R. K. O’Reilly, and P. J. Sadler, Faraday Discussions, 2014, 175, 229-240.
• Fabrication of crystals from single metal atoms
  N. P. E. Barry, A. Pitto-Barry, A. M. Sanchez, A. P. Dove, R. J. Procter, J. J. Soldevila-Barreda, N. Kirby, I. Hands-Portman, C. J. Smith, R. K. O’Reilly, R. Beanland, and P. J. Sadler, Nature Communications, 2014, 5, 3851.
• Synthetic strategies, sustainability and biological applications of malic acid-based polymers
  S. L. King, V. X. Truong, C. Kirchhoefer, A. Pitto-Barry, A. P. Dove, Green Materials, 2014, 2, 107-122
• Pluronic^® block-copolymers in medicine: From chemical and biological versatility to rationalisation and clinical advances
  A. Pitto-Barry, N. P. E. Barry, Polymer Chemistry, 2014, 5, 3291-3297.

• 100 years of metal coordination chemistry: from Alfred Werner to anticancer metallodrugs
  N. P. E. Barry and P. J. Sadler, Pure and Applied Chemistry, 2014, 86, 1897-1910.
• The Potent Oxidant Anticancer Activity of Organoiridium Catalysts
  Z. Liu, I. Romero-Canelón, B. Qamar, J. M. Hearn, A. Habtemariam, N. P. E. Barry, A. M. Pizarro, G. J. Clarkson, P. J. Sadler, Angewandte Chemie International Edition, 2014, 53, 3941–3946.
• A multinuclear ₁H, ₁₃C and ₁₁B solid-state MAS NMR study of 16- and 18-electron organometallic ruthenium and osmium carborane complexes
  N. P. E. Barry, T. F. Kemp, P. J. Sadler, J. V. Hanna, Dalton Transactions, 2014, 43, 4945-4949, part of a themed issue on Carboranes.
• Rational design of an arene ruthenium chlorin conjugate for in vivo anticancer activity
  M. Pernot, N. P. E. Barry, T. Bastogne, C. Frochot, M. Barberi-Heyob, B. Therrien, Inorganica Chimica Acta, 2014, 414, 134-140.
• Construction of DNA–polymer hybrids using intercalation interactions
  T. Wilks, A. Pitto-Barry, N. Kirby, E. Stulz and R. K. O’Reilly, Chemical Communications, 2014, 50, 1338-1340.
• Expanding the scope of the crystallization-driven self-assembly of polylactide-containing polymers
  A. Pitto-Barry, N. Kirby, A. P. Dove and R. K. O’Reilly, Polymer Chemistry, 2014, 5, 1427-1436.

2013

• Tuning the size of cylindrical micelles from poly(L-lactide)-b-poly(acrylic acid) diblock copolymers based on crystallization-driven self-assembly
  L. Sun, N. Petzetakis, A. Pitto-Barry, T. Schiller, N. Kirby, D. Keddie, B. Boyd, R. K. O’Reilly and A. P. Dove, Macromolecules, 2013, 46, 9074–9082.
• Challenges for Metals in Medicine: How Nanotechnology May Help to Shape the Future
  N. P. E. Barry, P. J. Sadler, ACS Nano, 2013, 7, 5654-5659.
• Exploration of the medical periodic table: towards new targets
  N. P. E. Barry, P. J. Sadler, Chemical Communications, 2013, 49, 5106-5131.
• Thermochromic organometallic complexes: experimental and theoretical studies of 16- to 18-electron interconversions of adducts of arene Ru(II) carboranes with aromatic amine ligands
  N. P. E. Barry, R. J. Deeth, G. J. Clarkson, I. Prokes, P. J. Sadler, Dalton Transactions, 2013, 42, 2580-2587.
• Metal-DNA Coordination Complexes
  A. M. Pizarro, N. P. E. Barry, P. J. Sadler, in Comprehensive Inorganic Chemistry II, Vol 3, Jan Reedijk and Kenneth Poeppelmeier, editors. Oxford: Elsevier; 2013, 752-784.

2012

• Systems biology approach for in vivo photodynamic therapy optimization of ruthenium-porphyrin compounds
  M. Pernot, T. Bastogne, N. P. E. Barry, B. Therrien, G. Koellensperger, S. Hann, V. Reshetov, M. Barberi-Heyob, Journal of Photochemistry and Photobiology B Biology, 2012, 117, 80-89.
• Enhancement of cytotoxicity by combining pyrenyl-dendrimers and arene ruthenium metalla-cages
  A. Pitto-Barry, O. Zava, P. J. Dyson, R. Deschenaux and B. Therrien, Inorganic Chemistry, 2012, 51, 7119-7124
• Dicarba-closo-dodecarborane-containing half-sandwich complexes of ruthenium, osmium, rhodium and iridium: biological relevance and synthetic strategies
  N. P. E. Barry, P. J. Sadler, Chemical Society Reviews, 2012, 41, 3264-3279.
• Delivery of Floxuridine Derivatives to Cancer Cells by Water-Soluble Organometallic Cages
  J. W. Yi, N. P. E. Barry, M. A. Furrer, O. Zava, P. J. Dyson, B. Therrien, B. H. Kim, Bioconjugate Chemistry, 2012, 23, 461-471.
• Organometallic Cages as Vehicles for Intracellular Release of Photosensitizers
  F. Schmitt, J. Freudenreich, N. P. E. Barry, L. Juillerat-Jeanneret, G. Süss-Fink, B. Therrien, Journal of the American Chemical Society, 2012, 134, 754-757.
• Encapsulation of hydrophobic pyrenyl-cycloplatinate complexes within a water-soluble arene ruthenium metalla-cage
  N. P. E. Barry, O. Zava, W. Wu, J. Zhaoc, B. Therrien, Inorganic Chemistry Communications, 2012, 18, 25-28.
• Encapsulation of inorganic and organic guest molecules into an organometallic hexacationic arene osmium metalla-prism: Synthesis, characterisation and anticancer activity
  N. P. E. Barry, O. Zava, P. J. Dyson, B. Therrien, Journal of Organometallic Chemistry, 2012, 705, 1-6.
• Efficient photodynamic therapy of cancer using chemotherapeutic porphyrin–ruthenium metalla-cubes
  F. Schmitt, N. P. E. Barry, L. Juillerat-Jeanneret, B. Therrien, Bioorganic and Medicinal Chemistry Letters, 2012, 22, 178-180.

2011

• Excellent Correlation between Drug Release and Portal Size in Metalla-Cage Drug-Delivery Systems
  N. P. E. Barry, O. Zava, P. J. Dyson, B. Therrien, Chemistry A European Journal, 2011, 17, 9669-9677.
• Anticancer activity of tetra-cationic arene ruthenium metalla-cycles
  N. P. E. Barry, F. Edafe, B. Therrien, Dalton Transactions, 2011, 40, 7172-7180.
• Encapsulation of pyrene-functionalised poly(benzyl ether) dendrons into an arene ruthenium metalla-prism
  A. Pitto-Barry, N. P. E. Barry, O. Zava, R. Deschenaux, B. Therrien, Chemistry An Asian Journal, 2011, 6, 1595-1603.
• Double Targeting of Tumours with Pyrenyl-Modified Dendrimers Encapsulated in an Arene-Ruthenium Metalla-Prism, A. Pitto-Barry, N. P. E. Barry, O. Zava, R. Deschenaux, P. J. Dyson, B. Therrien, Chemistry A European Journal, 2011, 17, 1966-1971.
• Ru²(CO)⁴(OOCR)²L² sawhorse-type complexes containing axial 5-(4-pyridyl)-10,15,20-triphenylporphyrin ligands
  M. Gras, N. P. E. Barry, B. Therrien, G. Süss-Fink, Inorganica Chimica Acta, 2011, 371, 59-62.

2010

• Synthesis, Characterisation and Anticancer Activity of Porphyrin Containing Organometallic Cubes
  N. P. E. Barry, O. Zava, P. J. Dyson, B. Therrien, Australian Journal of Chemistry, 2010, 63, 1529-1537.

• In- and out-of-cavity interactions by modulating the size of ruthenium metalla-rectangles
  N. P. E. Barry, J. Furrer, B. Therrien, Helvetica Chimica Acta, 2010, 93, 1313-1328.
• Anticancer activity of opened arene ruthenium metalla-assemblies
  N. P. E. Barry, O. Zava, J. Furrer, P. J. Dyson, B. Therrien, Dalton Transactions, 2010, 39, 5272-5277.
• Permanent encapsulation or host-guest behavior of aromatic molecules in hexanuclear arene ruthenium prisms
  J. Freudenreich, N. P. E. Barry, G. Süss-Fink, B. Therrien, European Journal of Inorganic Chemistry, 2010, 2400-2405.
• Anticancer activity of osmium metalla-rectangles
  N. P. E. Barry, F. Edafe, P. J. Dyson, B. Therrien, Dalton Transactions, 2010, 39, 2816-2820.
• Designing the host-guest properties of tetranuclear arene ruthenium metalla-rectangles to accommodate a pyrene molecule,
  N. P. E. Barry, J. Furrer, J. Freudenreich, G. Süss-Fink, B. Therrien, European Journal of Inorganic Chemistry, 2010, 725-728.

2009

• Interactions of ruthenium coordination cubes with DNA,
  N. P. E. Barry, N. H. Abd Karim, R. Vilar, B. Therrien, Dalton Transactions, 2009, 10717-10719.
• Host-guest chemistry in the hexanuclear arene ruthenium metalla-prismatic cage [Ru⁶(p-cymene)⁶(tpt)²(dhnq)³]₆₊,
  N. P. E. Barry, B. Therrien, European Journal of Inorganic Chemistry, 2009, 4695-4700.
• Highly efficient NMR enantiodiscrimination of chiral octanuclear metalla-boxes in polar solvent
  N. P. E. Barry, M. Austeri, J. Lacour, B. Therrien, Organometallics, 2009, 28, 4894-4897.
• Photochemical [2 + 2] cycloaddition of the olefinic double bonds in the supramolecular rectangle [Ru⁴(p-cymene)⁴(oxalato)²(4,4′-bipyridylethylene)²]₄₊
  N. P. E. Barry, B. Therrien, Inorganic Chemistry Communications, 2009, 12, 465-468.

2008

• Organometallic boxes built from 5,10,15,20-tetra(4-pyridyl)porphyrin panels and hydroxyquinonato-bridged diruthenium clips,
  N. P. E. Barry, P. Govindaswamy, J. Furrer, G. Süss-Fink, B. Therrien, Inorganic Chemistry Communications, 2008, 11, 1300-1303.

Patents

3. N. P. E. Barry, A. Pitto-Barry, J. J. Soldevila-Barreda, J. Cox, Antibiotics, 2020, P349270GB.

2. A. Pitto-Barry, and N. P. E. Barry, “CO absorber”, 2018, GB1806060.8, PCT/GB2019/051059.

1. A. Pitto-Barry, R. Beanland, P. J. Sadler and N. P. E. Barry, “Nanocrystals”, 2015, PCT/GB2015/051264.